Integrin-Linked Kinase Regulates Endothelial Cell Survival and Vascular Development

Integrin-linked kinase (ILK) is a phosphoinositide 3-kinase-dependent serine/threonine kinase that interacts with β integrins. Here we show that endothelial cell (EC)-specific deletion of ILK in mice confers placental insufficiency with decreased labyrinthine vascularization, yielding no viable offs...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Friedrich, Erik B., Liu, Emerson, Sinha, Sumita, Cook, Stuart, Milstone, David S., MacRae, Calum A., Mariotti, Massimo, Kuhlencordt, Peter J., Force, Thomas, Rosenzweig, Anthony, St-Arnaud, Rene, Dedhar, Shoukat, Gerszten, Robert E.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2004
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC515035/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15340074/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.18.8134-8144.2004
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