Genome Size and Structure Determine Efficiency of Postinternalization Steps and Gene Transfer of Capsid-Modified Adenovirus Vectors in a Cell-Type-Specific Manner

Adenovirus serotype 5 (Ad5) vectors containing Ad B-group fibers have become increasingly popular as gene transfer vectors because they efficiently transduce human cell types that are relatively refractory to Ad5 infection. So far, most B-group fiber-containing vectors have been first-generation vec...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Shayakhmetov, Dmitry M., Li, Zong-Yi, Gaggar, Anuj, Gharwan, Helen, Ternovoi, Vladimir, Sandig, Volker, Lieber, André
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Gene Therapy
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15331734/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.18.10009-10022.2004
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