Generation of Influenza A Virus NS2 (NEP) Mutants with an Altered Nuclear Export Signal Sequence

The NS2 (NEP) protein of influenza A virus contains a highly conserved nuclear export signal (NES) motif in its amino-terminal region ((12)ILMRMSKMQL(21), A/WSN/33), which is thought to be required for nuclear export of viral ribonucleoprotein complexes (vRNPs) mediated by a cellular export factor,...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Iwatsuki-Horimoto, Kiyoko, Horimoto, Taisuke, Fujii, Yutaka, Kawaoka, Yoshihiro
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Virus-Cell Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15331747/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.18.10149-10155.2004
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