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Role and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or β-amyloid

Neuron death during development and in Alzheimer’s disease (AD) is associated with aberrant regulation/induction of cell cycle proteins. However, the proximal events in this process are unknown. Cell cycle initiation requires dephosphorylation of cyclin-dependent kinases by cell division cycle 25A (...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Chatterjee, Nandini, Sanphui, Priyankar, Kemeny, Stav, Greene, Lloyd A, Biswas, Subhas C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149581/
https://ncbi.nlm.nih.gov/pubmed/28028440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.83
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