Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus

CD4(+) T cells develop distinct and often contrasting helper, regulatory, or cytotoxic activities. Typically a property of CD8(+) T cells, granzyme-mediated cytotoxic T cell (CTL) potential is also exerted by CD4(+) T cells. However, the conditions that induce CD4(+) CTLs are not entirely understood...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Donnarumma, Tiziano, Young, George R., Merkenschlager, Julia, Eksmond, Urszula, Bongard, Nadine, Nutt, Stephen L., Boyer, Claude, Dittmer, Ulf, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko, Bayer, Wibke, Kassiotis, George
Format: Artigo
Language:Inglês
Published: Cell Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149578/
https://ncbi.nlm.nih.gov/pubmed/27806296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.013
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