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Signal recognition particle mediates post-translational targeting in eukaryotes

Signal recognition particle (SRP) plays a central role in the delivery of classical secretory and membrane proteins to the endoplasmic reticulum (ER). All nascent chains studied to date dissociate from SRP once released from the ribosome, thereby supporting a strictly cotranslational mode of action...

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Autors principals: Abell, Benjamin M, Pool, Martin R, Schlenker, Oliver, Sinning, Irmgard, High, Stephen
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514945/
https://ncbi.nlm.nih.gov/pubmed/15229647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600281
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