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The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA

Tn7 transposition requires the assembly of a nucleoprotein complex containing four self-encoded proteins, transposon ends, and target DNA. Within this complex, TnsC, the molecular switch that regulates transposition, and TnsA, one part of the transposase, interact directly. Here, we demonstrate that...

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Autors principals: Ronning, Donald R, Li, Ying, Perez, Zhanita N, Ross, Philip D, Hickman, Alison Burgess, Craig, Nancy L, Dyda, Fred
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514928/
https://ncbi.nlm.nih.gov/pubmed/15257292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600311
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