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Phosphorylation and activation of Bub1 on unattached chromosomes facilitate the spindle checkpoint

The spindle checkpoint inhibits anaphase until all kinetochores have attached properly to spindle microtubules. The protein kinase Bub1 is an essential checkpoint component that resides at kinetochores during mitosis. It is shown herein that Xenopus Bub1 becomes hyperphosphorylated and the kinase is...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखक: Chen, Rey-Huei
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC514925/
https://ncbi.nlm.nih.gov/pubmed/15241477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600308
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