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Rapid double 8-nm steps by a kinesin mutant

The mechanism by which conventional kinesin walks along microtubules is poorly understood, but may involve alternate binding to the microtubule and hydrolysis of ATP by the two heads. Here we report a single amino-acid change that affects stepping by the motor. Under low force or low ATP concentrati...

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Detaylı Bibliyografya
Asıl Yazarlar: Higuchi, Hideo, Bronner, Christian Eric, Park, Hee-Won, Endow, Sharyn A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC514923/
https://ncbi.nlm.nih.gov/pubmed/15257294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600306
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