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Stereoselective Synthesis of 5-Epi-α-Sialosides Related to the Pseudaminic Acid Glycosides. Reassessment of the Stereoselectivity of the 5-Azido-5-deacetamidosialyl Thioglycosides and Use of Triflate as Nucleophile in the Zbiral Deamination of Sialic Acids

With a view to the eventual synthesis of glycosyl donors for the stereocontrolled synthesis of pseudaminic acid glycosides, the stereocontrolled synthesis of a d-glycero-d-gulo sialic acid adamantanylthioglycoside carrying an axial azide at the 5-position is described. The synthesis employs levulini...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Dhakal, Bibek, Buda, Szymon, Crich, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148678/
https://ncbi.nlm.nih.gov/pubmed/27806203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b02221
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