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Deficits in the Extinction of Ethanol-Seeking Behavior following Chronic Intermittent Ethanol Exposure are Attenuated with Positive Allosteric Modulation of mGlu5

Alcoholism is a chronic relapsing disorder characterized by periods of heavy alcohol consumption and unsuccessful attempts at abstinence. Relapse is one of the most problematic aspects in the treatment of alcoholism and is triggered by ethanol-associated cues. Extinction-based cue exposure therapies...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Gass, J. T., McGonigal, J.T., Chandler, L.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148675/
https://ncbi.nlm.nih.gov/pubmed/27725153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.10.005
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