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Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two apparently distinct neurodegenerative diseases, the former characterized by selective loss of motor neurons in the brain and spinal cord and the latter characterized by selective atrophy of frontal and temporal lobes. Over...

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Pubblicato in:Neurosci Lett
Autori principali: Wen, Xinmei, Westergard, Thomas, Pasinelli, Piera, Trotti, Davide
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148671/
https://ncbi.nlm.nih.gov/pubmed/27619540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.09.007
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