Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity.
The relationship between detrimental (cachectic) and beneficial (antitumor) effects of tumor necrosis factor (TNF) was studied in mice bearing murine tumors transfected to secrete human TNF. In vitro, the TNF-producing transfectants were resistant to the secreted TNF and grew at rates similar to tho...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2023898/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.9.3535 |
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