HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression

Reduced mitochondrial DNA copy number, mitochondrial DNA mutations or disruption of electron transfer chain complexes induce mitochondria-to-nucleus retrograde signaling, which induces global change in nuclear gene expression ultimately contributing to various human pathologies including cancer. Rec...

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Détails bibliographiques
Publié dans:Cell Discov
Auteurs principaux: Guha, Manti, Srinivasan, Satish, Guja, Kip, Mejia, Edison, Garcia-Diaz, Miguel, Johnson, F Brad, Ruthel, Gordon, Kaufman, Brett A, Rappaport, Eric F, Glineburg, M Rebecca, Fang, Ji-Kang, Klein Szanto, Andres, Nakagawa, Hiroshi, Basha, Jeelan, Kundu, Tapas, Avadhani, Narayan G
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148442/
https://ncbi.nlm.nih.gov/pubmed/27990297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.45
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