Inhibition of tumor growth in mice with severe combined immunodeficiency is mediated by heat shock protein 70 (Hsp70)-peptide–activated, CD94 positive natural killer cells

Previously, we reported that the major stress-inducible heat shock protein 70 (Hsp70) acts as a recognition structure for natural killer (NK) cells, if localized on the cell surface of tumor cells. Incubation of purified NK cells with low-dose interleukin (IL)-2 (100 IU/mL) plus recombinant Hsp70-pr...

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Bibliographic Details
Main Authors: Moser, Christian, Schmidbauer, Christin, Gürtler, Ulrich, Gross, Catharina, Gehrmann, Mathias, Thonigs, Gerald, Pfister, Karin, Multhoff, Gabriele
Format: Artigo
Language:Inglês
Published: Cell Stress Society International 2002
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC514836/
https://ncbi.nlm.nih.gov/pubmed/12653481
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