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Retinoid- and sodium-butyrate– induced decrease in heat shock protein 70 membrane-positive tumor cells is associated with reduced sensitivity to natural killer cell lysis, growth delay, and altered growth morphology

Human tumors frequently present heat shock protein 70 (Hsp70) on their cell membranes, whereas corresponding normal tissues fail to do so. Therefore, an Hsp70 membrane-positive phenotype provided a tumor-specific marker. Moreover, membrane-bound Hsp70 provides a target structure for the cytolytic at...

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Autori principali: Gehrmann, Mathias, Schönberger, Johann, Zilch, Tanja, Rossbacher, Lydia, Thonigs, Gerald, Eilles, Christoph, Multhoff, Gabriele
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Stress Society International 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176472/
https://ncbi.nlm.nih.gov/pubmed/16038410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-88R1.1
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