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The Role of GluN2C-Containing NMDA Receptors in Ketamine's Psychotogenic Action and in Schizophrenia Models

The NMDA receptor (NMDAR) hypofunction hypothesis of schizophrenia is supported by multiple lines of evidence. Notably, administration of the NMDAR antagonist, ketamine, to healthy human subjects has psychotogenic action, producing both positive and negative symptoms associated with schizophrenia. N...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Khlestova, Elizaveta, Johnson, Jon W., Krystal, John H., Lisman, John
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148234/
https://ncbi.nlm.nih.gov/pubmed/27807157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1203-16.2016
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