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The Role of GluN2C-Containing NMDA Receptors in Ketamine's Psychotogenic Action and in Schizophrenia Models

The NMDA receptor (NMDAR) hypofunction hypothesis of schizophrenia is supported by multiple lines of evidence. Notably, administration of the NMDAR antagonist, ketamine, to healthy human subjects has psychotogenic action, producing both positive and negative symptoms associated with schizophrenia. N...

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發表在:J Neurosci
Main Authors: Khlestova, Elizaveta, Johnson, Jon W., Krystal, John H., Lisman, John
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148234/
https://ncbi.nlm.nih.gov/pubmed/27807157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1203-16.2016
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