GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine

A single, low dose of the NMDA receptor antagonist ketamine produces rapid antidepressant actions in treatment-resistant depressed patients. Understanding the cellular mechanisms underlying this will lead to new therapies for treating major depression. NMDARs are heteromultimeric complexes formed th...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:eLife
Main Authors: Miller, Oliver H, Yang, Lingling, Wang, Chih-Chieh, Hargroder, Elizabeth A, Zhang, Yihui, Delpire, Eric, Hall, Benjamin J
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2014
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270067/
https://ncbi.nlm.nih.gov/pubmed/25340958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03581
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares