Two Isoforms of Yersinia pestis Plasminogen Activator Pla: Intraspecies Distribution, Intrinsic Disorder Propensity, and Contribution to Virulence

It has been shown previously that several endemic Y. pestis isolates with limited virulence contained the I259 isoform of the outer membrane protease Pla, while the epidemic highly virulent strains possessed only the T259 Pla isoform. Our sequence analysis of the pla gene from 118 Y. pestis subsp. m...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Dentovskaya, Svetlana V., Platonov, Mikhail E., Svetoch, Tat’yana E., Kopylov, Pavel Kh., Kombarova, Tat’yana I., Ivanov, Sergey A., Shaikhutdinova, Rima Z., Kolombet, Lyubov’ V., Chauhan, Sadhana, Ablamunits, Vitaly G., Motin, Vladimir L., Uversky, Vladimir N., Anisimov, Andrey P.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148098/
https://ncbi.nlm.nih.gov/pubmed/27936190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168089
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