Two Isoforms of Yersinia pestis Plasminogen Activator Pla: Intraspecies Distribution, Intrinsic Disorder Propensity, and Contribution to Virulence

It has been shown previously that several endemic Y. pestis isolates with limited virulence contained the I259 isoform of the outer membrane protease Pla, while the epidemic highly virulent strains possessed only the T259 Pla isoform. Our sequence analysis of the pla gene from 118 Y. pestis subsp. m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dentovskaya, Svetlana V., Platonov, Mikhail E., Svetoch, Tat’yana E., Kopylov, Pavel Kh., Kombarova, Tat’yana I., Ivanov, Sergey A., Shaikhutdinova, Rima Z., Kolombet, Lyubov’ V., Chauhan, Sadhana, Ablamunits, Vitaly G., Motin, Vladimir L., Uversky, Vladimir N., Anisimov, Andrey P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148098/
https://ncbi.nlm.nih.gov/pubmed/27936190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168089
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