Increased Bone Mass in Female Mice Lacking Mast Cell Chymase

Here we addressed the potential impact of chymase, a mast-cell restricted protease, on mouse bone phenotype. We show that female mice lacking the chymase Mcpt4 acquired a persistent expansion of diaphyseal bone in comparison with wild type controls, reaching a 15% larger diaphyseal cross sectional a...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Lind, Thomas, Gustafson, Ann-Marie, Calounova, Gabriela, Hu, Lijuan, Rasmusson, Annica, Jonsson, Kenneth B., Wernersson, Sara, Åbrink, Magnus, Andersson, Göran, Larsson, Sune, Melhus, Håkan, Pejler, Gunnar
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148084/
https://ncbi.nlm.nih.gov/pubmed/27936149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167964
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