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HbS Binding to GP1bα Activates Platelets in Sickle Cell Disease
Intravascular hemolysis increases the risk of thrombosis in hemolytic disorders. Our previous study showed that the binding of adult hemoglobin (HbA) to glycoprotein (GP) 1bα induced the activation of platelets. The elevated plasma Hb or platelet surface bound Hb positively correlated with platelet...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5148012/ https://ncbi.nlm.nih.gov/pubmed/27936141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167899 |
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