HbS Binding to GP1bα Activates Platelets in Sickle Cell Disease

Intravascular hemolysis increases the risk of thrombosis in hemolytic disorders. Our previous study showed that the binding of adult hemoglobin (HbA) to glycoprotein (GP) 1bα induced the activation of platelets. The elevated plasma Hb or platelet surface bound Hb positively correlated with platelet...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Annarapu, Gowtham K., Singhal, Rashi, Gupta, Avinash, Chawla, Sheetal, Batra, Harish, Seth, Tulika, Guchhait, Prasenjit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148012/
https://ncbi.nlm.nih.gov/pubmed/27936141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167899
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