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Molecular Evolution of PTEN Pseudogenes in Mammals

Phosphatase and tensin homolog (PTEN) is a tumor-suppressor gene. PTEN pseudogene (PTENp) acts as an endogenous RNA, which regulates its parental gene by competitively binding to the 3’ UTR of PTEN gene in the human. Despite the importance of this pseudogene, little is known about the molecular evol...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Tang, Jingsi, Ning, Ruihong, Zeng, Bo, Li, Ying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148010/
https://ncbi.nlm.nih.gov/pubmed/27936183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167851
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