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Molecular Evolution of PTEN Pseudogenes in Mammals

Phosphatase and tensin homolog (PTEN) is a tumor-suppressor gene. PTEN pseudogene (PTENp) acts as an endogenous RNA, which regulates its parental gene by competitively binding to the 3’ UTR of PTEN gene in the human. Despite the importance of this pseudogene, little is known about the molecular evol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tang, Jingsi, Ning, Ruihong, Zeng, Bo, Li, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148010/
https://ncbi.nlm.nih.gov/pubmed/27936183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167851
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