Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide

Human diploid fibroblasts (HDFs) exposed to subcytotoxic stresses under H(2)O(2), tert-butylhydroperoxide (t-BHP), and ethanol (EtOH) undergo stress-induced premature senescence (SIPS) characterized by many biomarkers of HDFs replicative senescence. Among these biomarkers are a growth arrest, an inc...

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Detalhes bibliográficos
Main Authors: Dumont, Patrick, Chainiaux, Florence, Eliaers, François, Petropoulou, Chariklia, Remacle, José, Koch-Brandt, Claudia, Gonos, Efstathios S., Toussaint, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Stress Society International 2002
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514799/
https://ncbi.nlm.nih.gov/pubmed/11892985
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