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A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions
Comprehensive delineation of complex cellular networks requires high-throughput interrogation of genetic interactions. To address this challenge, we describe the development of a multiplex combinatorial strategy to assess pairwise genetic interactions using CRISPR-Cas9 genome editing and next-genera...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5147906/ https://ncbi.nlm.nih.gov/pubmed/27936040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167617 |
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