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A Sweep of Earth’s Virome Reveals Host-Guided Viral Protein Structural Mimicry and Points to Determinants of Human Disease

Viruses deploy genetically encoded strategies to coopt host machinery and support viral replicative cycles. Here, we use protein structure similarity to scan for molecular mimicry, manifested by structural similarity between viral and endogenous host proteins, across thousands of cataloged viruses a...

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Bibliografische gegevens
Gepubliceerd in:Cell Syst
Hoofdauteurs: Lasso, Gorka, Honig, Barry, Shapira, Sagi D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier Inc. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552982/
https://ncbi.nlm.nih.gov/pubmed/33053371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.09.006
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