Dual Specificity Phosphatase 5 Is Essential for T Cell Survival

The mitogen-activated protein kinase (MAPK) pathway regulates many key cellular processes such as differentiation, apoptosis, and survival. The final proteins in this pathway, ERK1/2, are regulated by dual specificity phosphatase 5 (DUSP5). DUSP5 is a nuclear, inducible phosphatase with high affinit...

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Опубликовано в: :PLoS One
Главные авторы: Kutty, Raman G., Xin, Gang, Schauder, David M., Cossette, Stephanie M., Bordas, Michelle, Cui, Weiguo, Ramchandran, Ramani
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147890/
https://ncbi.nlm.nih.gov/pubmed/27936095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167246
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