BRCAness and Prognosis in Triple-Negative Breast Cancer Patients Treated with Neoadjuvant Chemotherapy

BRCAness is defined as the set of traits in which BRCA1 dysfunction, arising from gene mutation, methylation or deletion, results in DNA repair deficiency. In the present study, we addressed BRCAness, therapeutic efficacy, recurrence, and survival in patients with triple negative breast cancer (TNBC...

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Udgivet i:PLoS One
Main Authors: Tanino, Hirokazu, Kosaka, Yoshimasa, Nishimiya, Hiroshi, Tanaka, Youko, Minatani, Naoko, Kikuchi, Mariko, Shida, Akiko, Waraya, Mina, Katoh, Hiroshi, Enomoto, Takumo, Sengoku, Norihiko, Kajita, Sabine, Hoffman, Robert M., Watanabe, Masahiko
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147808/
https://ncbi.nlm.nih.gov/pubmed/27935989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165721
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