BRCAness and Prognosis in Triple-Negative Breast Cancer Patients Treated with Neoadjuvant Chemotherapy

BRCAness is defined as the set of traits in which BRCA1 dysfunction, arising from gene mutation, methylation or deletion, results in DNA repair deficiency. In the present study, we addressed BRCAness, therapeutic efficacy, recurrence, and survival in patients with triple negative breast cancer (TNBC...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tanino, Hirokazu, Kosaka, Yoshimasa, Nishimiya, Hiroshi, Tanaka, Youko, Minatani, Naoko, Kikuchi, Mariko, Shida, Akiko, Waraya, Mina, Katoh, Hiroshi, Enomoto, Takumo, Sengoku, Norihiko, Kajita, Sabine, Hoffman, Robert M., Watanabe, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147808/
https://ncbi.nlm.nih.gov/pubmed/27935989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165721
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