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Expression of the RND-Type Efflux Pump AdeABC in Acinetobacter baumannii Is Regulated by the AdeRS Two-Component System

The AdeABC pump of Acinetobacter baumannii BM4454, which confers resistance to various antibiotic classes including aminoglycosides, is composed of the AdeA, AdeB, and AdeC proteins; AdeB is a member of the RND superfamily. The adeA, adeB, and adeC genes are contiguous and adjacent to adeS and adeR,...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Marchand, Isabelle, Damier-Piolle, Laurence, Courvalin, Patrice, Lambert, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15328088/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.9.3298-3304.2004
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