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Structural Mechanism for Cargo Recognition by the Retromer Complex
Retromer is a multi-protein complex that recycles transmembrane cargo from endosomes to the trans-Golgi network and the plasma membrane. Defects in retromer impair various cellular processes, and underlie some forms of Alzheimer’s disease and Parkinson’s disease. Although retromer was discovered ove...
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| Udgivet i: | Cell |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5147500/ https://ncbi.nlm.nih.gov/pubmed/27889239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.056 |
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