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Structural Mechanism for Cargo Recognition by the Retromer Complex

Retromer is a multi-protein complex that recycles transmembrane cargo from endosomes to the trans-Golgi network and the plasma membrane. Defects in retromer impair various cellular processes, and underlie some forms of Alzheimer’s disease and Parkinson’s disease. Although retromer was discovered ove...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Lucas, María, Gershlick, David C., Vidaurrazaga, Ander, Rojas, Adriana L., Bonifacino, Juan S., Hierro, Aitor
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147500/
https://ncbi.nlm.nih.gov/pubmed/27889239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.056
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