An Internationally Spread Clone of Streptococcus pneumoniae Evolves from Low-Level to Higher-Level Penicillin Resistance by Uptake of Penicillin-Binding Protein Gene Fragments from Nonencapsulated Pneumococci

Low-level penicillin resistance in an international Streptococcus pneumoniae serotype 19F clone emerging in Switzerland was characterized by mutations in the penicillin-binding protein PBP2x. Some isolates of this clone had evolved to higher resistance levels (penicillin MICs of 0.094 and 1 μg/ml),...

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Hlavní autoři: Hauser, Christoph, Aebi, Suzanne, Mühlemann, Kathrin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC514746/
https://ncbi.nlm.nih.gov/pubmed/15328127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3563-3566.2004
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