Low-Level Resistance to Rifampin in Streptococcus pneumoniae

Rifampin is recommended for combination therapy of meningitis due to β-lactam-resistant Streptococcus pneumoniae. High-level rifampin resistance (MIC, ≥4 mg/liter) has been mapped to point mutations in clusters I and III of rpoB of the pneumococcus. The molecular basis of low-level resistance (MICs,...

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Main Authors: Meier, Patricia Stutzmann, Utz, Silvia, Aebi, Suzanne, Mühlemann, Kathrin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC149310/
https://ncbi.nlm.nih.gov/pubmed/12604513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.863-868.2003
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