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Paradoxical Effect of Caspofungin: Reduced Activity against Candida albicans at High Drug Concentrations

Resistance problems with caspofungin, an echinocandin inhibitor of fungal cell wall glucan synthesis, have been rare. We noted paradoxical turbid growth of Candida albicans isolates in broth in some high (supra-MIC) concentrations. Among isolates submitted for susceptibility testing and screened at...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Stevens, David A., Espiritu, Marife, Parmar, Rachana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15328104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.9.3407-3411.2004
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