Paradoxical Effect of Caspofungin: Reduced Activity against Candida albicans at High Drug Concentrations

Resistance problems with caspofungin, an echinocandin inhibitor of fungal cell wall glucan synthesis, have been rare. We noted paradoxical turbid growth of Candida albicans isolates in broth in some high (supra-MIC) concentrations. Among isolates submitted for susceptibility testing and screened at...

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Bibliographic Details
Main Authors: Stevens, David A., Espiritu, Marife, Parmar, Rachana
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC514730/
https://ncbi.nlm.nih.gov/pubmed/15328104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3407-3411.2004
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