Use and comparison of different internal ribosomal entry sites (IRES) in tricistronic retroviral vectors

BACKGROUND: Polycistronic retroviral vectors that contain several therapeutic genes linked via internal ribosome entry sites (IRES), provide new and effective tools for the co-expression of exogenous cDNAs in clinical gene therapy protocols. For example, tricistronic retroviral vectors could be used...

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Autors principals: Douin, Victorine, Bornes, Stephanie, Creancier, Laurent, Rochaix, Philippe, Favre, Gilles, Prats, Anne-Catherine, Couderc, Bettina
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514710/
https://ncbi.nlm.nih.gov/pubmed/15279677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-4-16
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