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Matching for the nonconventional MHC-I MICA gene significantly reduces the incidence of acute and chronic GVHD
Graft-versus-host disease (GVHD) is among the most challenging complications in unrelated donor hematopoietic cell transplantation (HCT). The highly polymorphic MHC class I chain–related gene A, MICA, encodes a stress-induced glycoprotein expressed primarily on epithelia. MICA interacts with the inv...
Shranjeno v:
izdano v: | Blood |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society of Hematology
2016
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5147017/ https://ncbi.nlm.nih.gov/pubmed/27549307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-719070 |
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