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Structures of human mitofusin 1 provide insight into mitochondrial tethering
Mitochondria undergo fusion and fission. The merging of outer mitochondrial membranes requires mitofusin (MFN), a dynamin-like GTPase. How exactly MFN mediates membrane fusion is poorly understood. Here, we determined crystal structures of a minimal GTPase domain (MGD) of human MFN1, including the p...
Guardat en:
| Publicat a: | J Cell Biol |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5147005/ https://ncbi.nlm.nih.gov/pubmed/27920125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201609019 |
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