EphA2 is a functional receptor for the growth factor progranulin

Although the growth factor progranulin was discovered more than two decades ago, the functional receptor remains elusive. Here, we discovered that EphA2, a member of the large family of Ephrin receptor tyrosine kinases, is a functional signaling receptor for progranulin. Recombinant progranulin boun...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Neill, Thomas, Buraschi, Simone, Goyal, Atul, Sharpe, Catherine, Natkanski, Elizabeth, Schaefer, Liliana, Morrione, Andrea, Iozzo, Renato V.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146997/
https://ncbi.nlm.nih.gov/pubmed/27903606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603079
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