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Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics

BACKGROUND: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include arbitrary pseudoknots. For restricted classes of pseudoknots, several polynomial time algorithms have been designed, where...

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Detalhes bibliográficos
Main Authors: Reeder, Jens, Giegerich, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514697/
https://ncbi.nlm.nih.gov/pubmed/15294028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-5-104
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