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Structure of the RBM7–ZCCHC8 core of the NEXT complex reveals connections to splicing factors
The eukaryotic RNA exosome participates extensively in RNA processing and degradation. In human cells, three accessory factors (RBM7, ZCCHC8 and hMTR4) interact to form the nuclear exosome targeting (NEXT) complex, which directs a subset of non-coding RNAs for exosomal degradation. Here we elucidate...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5146272/ https://ncbi.nlm.nih.gov/pubmed/27905398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13573 |
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