Caricamento...

Promoter-proximal polyadenylation sites reduce transcription activity

Gene expression relies on the functional communication between mRNA processing and transcription. We previously described the negative impact of a point-mutated splice donor (SD) site on transcription. Here we demonstrate that this mutation activates an upstream cryptic polyadenylation (CpA) site, w...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Andersen, Pia K., Lykke-Andersen, Søren, Jensen, Torben Heick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465738/
https://ncbi.nlm.nih.gov/pubmed/23028143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.189126.112
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !