Ménage-à-Trois: The Ratio of Bicarbonate to CO(2) and the pH Regulate the Capacity of Neutrophils to Form NETs

In this study, we identified and characterized the potential of a high ratio of bicarbonate to CO(2) and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation. Both experimental settings increased the rate of spontaneous NET release and potenti...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Maueröder, Christian, Mahajan, Aparna, Paulus, Susanne, Gößwein, Stefanie, Hahn, Jonas, Kienhöfer, Deborah, Biermann, Mona H., Tripal, Philipp, Friedrich, Ralf P., Munoz, Luis E., Neurath, Markus F., Becker, Christoph, Schett, Georg Andreas, Herrmann, Martin, Leppkes, Moritz
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145884/
https://ncbi.nlm.nih.gov/pubmed/28018350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00583
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