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Ad26/MVA Therapeutic Vaccination with TLR7 Stimulation in SIV-Infected Rhesus Monkeys

The development of immunologic interventions that can target the viral reservoir in HIV-1-infected individuals is a major goal of the HIV-1 cure field(1,2). However, little evidence exists that the viral reservoir can be sufficiently targeted to improve virologic control following discontinuation of...

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Publicado en:Nature
Main Authors: Borducchi, Erica N., Cabral, Crystal, Stephenson, Kathryn E., Liu, Jinyan, Abbink, Peter, Ng’ang’a, David, Nkolola, Joseph P., Brinkman, Amanda L., Peter, Lauren, Lee, Benjamin C., Jimenez, Jessica, Jetton, David, Mondesir, Jade, Mojta, Shanell, Chandrashekar, Abishek, Molloy, Katherine, Alter, Galit, Gerold, Jeff M., Hill, Alison L., Lewis, Mark G., Pau, Maria G., Schuitemaker, Hanneke, Hesselgesser, Joseph, Geleziunas, Romas, Kim, Jerome H., Robb, Merlin L., Michael, Nelson L., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145754/
https://ncbi.nlm.nih.gov/pubmed/27841870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20583
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