Nano-particle Delivery of Brain Derived Neurotrophic Factor after Focal Cerebral Ischemia Reduces Tissue Injury and Enhances Behavioral Recovery

BACKGROUND: Low levels of brain-derived neurotrophic factor (BDNF) are linked to delayed neurological recovery, depression, and cognitive impairment following stroke. Supplementation with BDNF reverses these effects. Unfortunately, systemically administered BDNF in its native form has minimal therap...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Harris, Nia M, Ritzel, Rodney, Mancini, Nikolas, Jiang, Yuhang, Yi, Xiang, Manickam, Devika S, Banks, William A., Kabanov, Alexander V, McCullough, Louise D, Verma, Rajkumar
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145740/
https://ncbi.nlm.nih.gov/pubmed/27619636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2016.09.003
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