Loss of Skeletal Muscle HIF-1α Results in Altered Exercise Endurance

The physiological flux of oxygen is extreme in exercising skeletal muscle. Hypoxia is thus a critical parameter in muscle function, influencing production of ATP, utilization of energy-producing substrates, and manufacture of exhaustion-inducing metabolites. Glycolysis is the central source of anaer...

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Main Authors: Mason, Steven D, Howlett, Richard A, Kim, Matthew J, Olfert, I. Mark, Hogan, Michael C, McNulty, Wayne, Hickey, Reed P, Wagner, Peter D, Kahn, C. Ronald, Giordano, Frank J, Johnson, Randall S
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2004
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514537/
https://ncbi.nlm.nih.gov/pubmed/15328538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020288
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