Colorectal cancers with microsatellite instability display mRNA expression signatures characteristic of increased immunogenicity

BACKGROUND: Colorectal cancers displaying high-degree microsatellite instability (MSI-H) have an improved prognosis compared to microsatellite stable (MSS) cancers. The observation of pronounced lymphocytic infiltrates suggests that MSI-H cancers are inherently more immunogenic. We aimed to compare...

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Detalhes bibliográficos
Main Authors: Banerjea, Ayan, Ahmed, Shafi, Hands, Rebecca E, Huang, Fei, Han, Xia, Shaw, Peter M, Feakins, Roger, Bustin, Stephen A, Dorudi, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514528/
https://ncbi.nlm.nih.gov/pubmed/15298707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-21
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